Intravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or undergoing clinical trials. The technique of prolonged intravenous delivery in conscious, free-moving animal models has broadened the opportunity to study and evaluate the safety and efficacy of these therapeutic products. With contributions from an international selection of authors who are leaders in commercial infusion technology, Non-Clinical Vascular Infusion Technology, Volume II: The Techniques provides a current account of the techniques involved in all the major laboratory animal species for conducting successful vascular infusion studies with xenobiotics. Following in the footsteps of the highly praised Handbook of Pre-Clinical Continuous Intravenous Infusion, this new volume covers both up-to-date procedures and equipment. It is organized by species, including all those commonly used in pre-clinical studies: rat, mouse, dog, minipig, large primate, and marmoset. There are also chapters on juvenile studies and reproductive toxicity studies. Each section addresses the selection of the best model, surgical and non-surgical best practices, practical techniques, equipment selection, and commonly encountered background pathologies. Using a fresh approach, the authors identify best practices to be shared across the industry, and provide guidance on choices for the most acceptable methodologies from an animal welfare perspective. This volume, along with Volume I: The Science, provides a foundation of knowledge on infusion technology and its importance for safe clinical use of substances via this route of delivery. Features: Emphasizes best practices in accordance with the 3Rsreduction, refinement, and replacement of animal usage in laboratories Presents step-by-step procedures and practical tips covering a wide range of common animal models, augmented by the liberal use of illustrations Covers modern practices and procedures in accordance with up-to-date equipment development <br><br> Autorid: Owen P. Green, Guy Healing <br>
'Holgate guides us expertly and with a deft touch along the journey towards the holy grail of unlimited energy for all.' - JIM AL-KHALILI 'What is nuclear fusion? In clear and accessible language, this book explains the basics and the hope for the future. A valuable addition to the Hot Science series.' - JOHN GRIBBIN Could the Sun hold the key to a future of clean energy? Since the 1950s, scientists have attempted to harness nuclear fusion - the process that creates the Sun's energy - to generate near-limitless amounts of electricity. But the fact that we still have no fusion power plants is testament to the complexities of the challenge. Now, the deepening climate crisis means that researchers around the world are in a race to create a mini-Sun here on Earth. The glittering prize is an energy source that emits no greenhouse gases and could solve energy equity and supply issues at a stroke. Sharon Ann Holgate, a former Young Professional Physicist of the Year, tells the compelling story of the ongoing scientific quest for a revolutionary new era of green energy production. <br><br> Autorid: Sharon Ann Holgate <br>
GTIN: 9788498485202Language teaching & learning material & coursework
Estructura del libro: El Libro del alumno consta de diecinueve unidades didácticas más dos unidades de repaso. Incluye: Libro del alumno + CD de audio Extensión digital en la ELEteca con material extra descargable y gratuito para el profesor y el estudiante. Materiales que componen nuevo sma Fusión A1+A2: Libro del alumno + CD. Libro de ejercicios + CD. Libro del profesor. Guía Maestra Digital.
nuevo PRISMA fusión A1+A2 es un curso de espańol que sigue los criterios y recomendaciones del Marco común europeo de referencia para las lenguas (MCER) y se dirige a aquellos alumnos que requieren de un curso más intensivo y dinámico que les ayude a alcanzar los objetivos fundamentales de los niveles A1 y A2 (etapa Usuario Básico) y les inicie en los contenidos de nivel B1.El Libro del profesor es una guía completa que incluye dinámicas y alternativas a las actividades propuestas en el Libro del alumno, justificación metodológica de las mismas, fichas y proyecciones, solucionario y transcripciones de las actividades, referencias cruzadas al libro de ejercicios..., y referencias cruzadas al material que aparece en la ELEteca.El Libro del profesor es una guía fácil e intuitiva que permitirá localizar de manera inmediata y completa toda la información y material complementario para preparar las clases de manera rápida y eficaz.El docente encontrará material en papel y en soporte digital (ELEteca), de manera que se pueda actualizar y complementar siempre que sea necesario.El material extra de la ELEteca es proyectable e imprimible y aparece referenciado en la secuencia didáctica mediante una serie de símbolos gráficos o iconos.El profesor contará en la ELEteca con tres apéndices en los que se trabajará el componente estratégico en el aprendizaje de ELE (con las actividades del Libro del alumno), el aprendizaje cooperativo en clase (conceptualización y dinámicas con las actividades del alumno) y las emociones en clase de ELE (elaborado por Rafael Bizquerra).
GTIN: 9788498485226Language teaching & learning material & coursework
Incluye: Libro + CD: 19 unidades de actividades. Apéndice gramatical. CD de audio. Transcripciones. Solucionario.ELEteca, Extensión digital: glosario, prácticas interactivas, actividades colaborativas (foros y wikis),Materiales que componen nuevo Prisma Fusión A1 + A2: Libro del alumno + CD.Recursos extras para el alumno en la ELEteca. Libro de ejercicios + CD. Libro del profesor. Recursos extras para el profesor en la ELEteca. Guía Maestra Digital (GMD).
This book is the second edition of Numerical methods for diffusion phenomena in building physics: a practical introduction originally published by PUCPRESS (2016). It intends to stimulate research in simulation of diffusion problems in building physics, by providing an overview of mathematical models and numerical techniques such as the finite difference and finite-element methods traditionally used in building simulation tools. Nonconventional methods such as reduced order models, boundary integral approaches and spectral methods are presented, which might be considered in the next generation of building-energy-simulation tools. In this reviewed edition, an innovative way to simulate energy and hydrothermal performance are presented, bringing some light on innovative approaches in the field. <br><br> Autorid: Nathan Mendes, Marx Chhay, Julien Berger, Denys Dutykh <br>
Tootekood: A70 BLACK REDGTIN: 6974028140175Headphones
Oneodio Fusion A70 wireless headphones (black and red)Are you looking for a professional piece of equipment that will also serve your everyday needs? The OneOdio A70 headphones are the device you've been looking for! They are equally suitable for DJ and as everyday headphones. You will connect them to various equipment like phones, tablets, speakers or electric guitars. Want to get rid of tangled wires? This problem will disappear with the wireless connection of the headphones. What's more, the special design will make their use very comfortable.Multiple connection optionsYou can connect OneOdio headphones exactly the way you like. One cable with a 3.5mm to 6.35mm tip gives you the opportunity to connect equally with phones, tablets and laptops, but also with electric guitars or mixers. What's more, special technology will allow two people to listen to the same music simultaneously on different equipment. Want to dispense with tangled cables? Bluetooth 5.2 technology, with which the headphones are equipped, will allow you to conveniently connect wirelessly.Long-lasting operationWant to enjoy the work of the headphones without limits? Opt for a wired connection using the special cable you'll find in the set. However, if you opt for a wireless connection, you can enjoy long operation, up to 50 hours. Such a long operating time is due to a Li-ion battery with a capacity of 950 mAh. This makes the equipment ideal equally for everyday use and the work of a professional DJ.High qualityWant to enjoy great sound, no matter which way you choose to connect? OneOdio A70 headphones can guarantee you that! What's more, you don't have to worry about accidentally pulling out the cable, as you can lock it into the headphones by twisting it. Convenient control of the equipment will allow you to use the buttons on the side. The headphones are also equipped with noise cancellation technology, so that any of your phone conversations will always be understandable.Convenience of useIf you're looking for comfortable equipment, choose the A70 headphones. The headband, so that you can fit it to the size of your head, is adjustable. What's more, the earcups themselves have the ability to rotate 90 degrees. For better storage and transportation, the headphones are foldable, and a pouch has been included. You can wear the OneOdio gear for many hours, as its earcups are very soft, so they will be comfortable to wear.Included:A70 headphones6.35mm to 3.5mm cable x 13.5mm audio cable x 1USB charging cableUser manualBag ManufacturerOneOdioModelA70ConnectivityAudio cable 3.5 mm / 6.35 mm, Bluetooth 5.2Wireless operating timeUp to 50 hoursBatteryLi-ion, 950 mAhColorBlack and red
Oneodio Fusion A70 wireless headphones (black)Are you looking for a professional piece of equipment that will also serve your everyday needs? The OneOdio A70 headphones are the device you've been looking for! They are equally suitable for DJ and as everyday headphones. You will connect them to various equipment like phones, tablets, speakers or electric guitars. Want to get rid of tangled wires? This problem will disappear with the wireless connection of the headphones. What's more, the special design will make their use very comfortable.Multiple connection optionsYou can connect OneOdio headphones exactly the way you like. One cable with a 3.5mm to 6.35mm tip gives you the opportunity to connect equally with phones, tablets and laptops, but also with electric guitars or mixers. What's more, special technology will allow two people to listen to the same music simultaneously on different equipment. Want to dispense with tangled cables? Bluetooth 5.2 technology, with which the headphones are equipped, will allow you to conveniently connect wirelessly.Long-lasting operationWant to enjoy the work of the headphones without limits? Opt for a wired connection using the special cable you'll find in the set. However, if you opt for a wireless connection, you can enjoy long operation, up to 50 hours. Such a long operating time is due to a Li-ion battery with a capacity of 950 mAh. This makes the equipment ideal equally for everyday use and the work of a professional DJ.High qualityWant to enjoy great sound, no matter which way you choose to connect? OneOdio A70 headphones can guarantee you that! What's more, you don't have to worry about accidentally pulling out the cable, as you can lock it into the headphones by twisting it. Convenient control of the equipment will allow you to use the buttons on the side. The headphones are also equipped with noise cancellation technology, so that any of your phone conversations will always be understandable.Convenience of useIf you're looking for comfortable equipment, choose the A70 headphones. The headband, so that you can fit it to the size of your head, is adjustable. What's more, the earcups themselves have the ability to rotate 90 degrees. For better storage and transportation, the headphones are foldable, and a pouch has been included. You can wear the OneOdio gear for many hours, as its earcups are very soft, so they will be comfortable to wear.Included:A70 headphones6.35mm to 3.5mm cable x 13.5mm audio cable x 1USB charging cableUser manualBag ManufacturerOneOdioModelA70ConnectivityAudio cable 3.5 mm / 6.35 mm, Bluetooth 5.2Wireless operating timeUp to 50 hoursBatteryLi-ion, 950 mAhColorBlack
Oneodio Fusion A70 wireless headphones (blue)Are you looking for a professional piece of equipment that will also serve your everyday needs? The OneOdio A70 headphones are the device you've been looking for! They are equally suitable for DJs and as everyday headphones. You will connect them to various equipment like phones, tablets, speakers or electric guitars. Want to get rid of tangled wires? This problem will disappear with the wireless connection of the headphones. What's more, the special design will make their use very comfortable.Multiple connection optionsYou can connect OneOdio headphones exactly the way you like. One cable with a 3.5mm to 6.35mm tip gives you the opportunity to connect equally with phones, tablets and laptops, but also with electric guitars or mixers. What's more, special technology will allow two people to listen to the same music simultaneously on different equipment. Want to dispense with tangled cables? Bluetooth 5.2 technology, with which the headphones are equipped, will allow you to conveniently connect wirelessly.Long-lasting operationWant to enjoy the work of the headphones without limits? Opt for a wired connection using the special cable you'll find in the set. However, if you opt for a wireless connection, you can enjoy long operation, up to 50 hours. Such a long operating time is due to a Li-ion battery with a capacity of 950 mAh. This makes the equipment ideal equally for everyday use and the work of a professional DJ.High qualityWant to enjoy great sound, no matter which way you choose to connect? OneOdio A70 headphones can guarantee you that! What's more, you don't have to worry about accidentally pulling out the cable, as you can lock it into the headphones by twisting it. Convenient control of the equipment will allow you to use the buttons on the side. The headphones are also equipped with noise cancellation technology, so that any of your phone conversations will always be understandable.Convenience of useIf you're looking for comfortable equipment, choose the A70 headphones. The headband, so that you can fit it to the size of your head, is adjustable. What's more, the earcups themselves have the ability to rotate 90 degrees. For better storage and transportation, the headphones are foldable, and a pouch has been included. You can wear the OneOdio gear for many hours, as its earcups are very soft, so they will be comfortable to wear.Included:A70 headphones6.35mm to 3.5mm cable x 13.5mm audio cable x 1USB charging cableUser manualBag ManufacturerOneOdioModelA70ConnectivityAudio cable 3.5 mm / 6.35 mm, Bluetooth 5.2Wireless operating timeUp to 50 hoursBatteryLi-ion, 950 mAhColorBlue
Oneodio Fusion A70 wireless headphones (brown)Are you looking for a professional piece of equipment that will also serve your everyday needs? The OneOdio A70 headphones are the device you've been looking for! They are equally suitable for DJ and as everyday headphones. You will connect them to various equipment like phones, tablets, speakers or electric guitars. Want to get rid of tangled wires? This problem will disappear with the wireless connection of the headphones. What's more, the special design will make their use very comfortable.Multiple connection optionsYou can connect OneOdio headphones exactly the way you like. One cable with a 3.5mm to 6.35mm tip gives you the opportunity to connect equally with phones, tablets and laptops, but also with electric guitars or mixers. What's more, special technology will allow two people to listen to the same music simultaneously on different equipment. Want to dispense with tangled cables? Bluetooth 5.2 technology, with which the headphones are equipped, will allow you to conveniently connect wirelessly.Long-lasting operationWant to enjoy the work of the headphones without limits? Opt for a wired connection using the special cable you'll find in the set. However, if you opt for a wireless connection, you can enjoy long operation, up to 50 hours. Such a long operating time is due to a Li-ion battery with a capacity of 950 mAh. This makes the equipment ideal equally for everyday use and the work of a professional DJ.High qualityWant to enjoy great sound, no matter which way you choose to connect? OneOdio A70 headphones can guarantee you that! What's more, you don't have to worry about accidentally pulling out the cable, as you can lock it into the headphones by twisting it. Convenient control of the equipment will allow you to use the buttons on the side. The headphones are also equipped with noise cancellation technology, so that any of your phone conversations will always be understandable.Convenience of useIf you're looking for comfortable equipment, choose the A70 headphones. The headband, so that you can fit it to the size of your head, is adjustable. What's more, the earcups themselves have the ability to rotate 90 degrees. For better storage and transportation, the headphones are foldable, and a pouch has been included. You can wear the OneOdio gear for many hours, as its earcups are very soft, so they will be comfortable to wear.Included:A70 headphones6.35mm to 3.5mm cable x 13.5mm audio cable x 1USB charging cableUser manualBag ManufacturerOneOdioModelA70ConnectivityAudio cable 3.5 mm / 6.35 mm, Bluetooth 5.2Wireless operating timeUp to 50 hoursBatteryLi-ion, 950 mAhColorBrown
Oneodio Fusion A70 wireless headphones (gold)Are you looking for headphones that will serve not only for listening to music on the phone, but also as professional DJ equipment? OneOdio headphones will be an excellent choice! Using special audio cables, you can connect them not only to your smartphone and tablet, but also to your speakers or guitar. Don't like tangled cables? This problem will also disappear, thanks to the possibility of wire-free connection of equipment. In addition, they will also be comfortable to use thanks to their excellent design.Multiple connection optionsOneOdio headphones have multiple connection options. With a single 3.5mm to 6.35mm cable, you can connect them equally to laptops, tablets and phones, but also to an electric guitar, AMP or audio interfaces. In addition, special technology will allow two people to simultaneously listen to the same music on two different devices. Tired of tangled cables? With the ability to connect the headphones wirelessly via Bluetooth 5.2, you can forget about this problem!Long working timeConnecting the headphones via a dedicated cable, you can use them without limits. If you choose a wireless connection, you can enjoy their long operation, up to 50 hours. They owe this to their large Li-ion battery with a capacity of 950 mAh. This makes them the ideal equipment for a professional DJ.Excellent qualityThe OneOdio A70 headphones will give you excellent sound with every connection. When you choose a wired connection, you can lock the plug so it won't disconnect at the least opportune moment. What's more, convenient buttons on the side of the headphones allow you to use them comfortably. They're also equipped with noise-canceling technology so that when you're on the phone, your caller can hear every word you say.Comfortable useThe A70 headphones were created with comfort in mind. The headband is adjustable so that you are able to adjust the equipment to fit your head properly. What's more, you can freely rotate the ear cups to a 90-degree angle, and the whole equipment can be folded. For better storage and transportation, make use of the bag that comes with the set. You also don't have to worry about wearing the headphones for a long time, as their earcups are very soft, making them very comfortable to use.Included:A70 headphones6.35mm to 3.5mm cable x 13.5mm audio cable x 1USB charging cable x 1User manualBag ManufacturerOneOdioModelA70ConnectivityAudio cable 3.5 mm / 6.35 mm, Bluetooth 5.2Wireless operating timeUp to 50 hoursBatteryLi-ion, 950 mAhColorGold
Oneodio Fusion A70 wireless headphones (pink)Are you recording podcasts and looking for a piece of equipment that will help you do that? At the same time, do you also want to use it for everyday music listening? OneOdio headphones are the equipment for you! You can connect to them equally phones, iPads, laptops, but also electric guitars, AMPs or audio interfaces. Want to get rid of tangled cables? Thanks to Bluetooth 5.2 technology, this problem will disappear! In addition, the use of OneOdio headphones will be more comfortable, thanks to the special design.Various connectivity optionsWith OneOdio headphones you will be able to listen to music exactly as you like. A cable with a 3.5mm to 6.35mm tip will give you the ability to connect a variety of equipment including a tablet phone, iPad, electric guitar, AMP and audio interfaces. In addition, thanks to a special technology, two people will be able to listen to the same song, at the same time, on two different devices. Do you want to do away with cables? With OneOdio it's possible, as these headphones are equipped with Bluetooth 5.2 technology for convenient wireless connection.Long working timeWorking long hours on podcast recordings? You don't have to nervously glance at the time anymore, because the wired connection gives you the opportunity to work without limits! However, do you prefer a wireless connection? Here you don't have to worry either, as the 950 mAh Li-ion battery life is as much as 50 hours. From today nothing will limit you anymore!High qualityEnjoy great sound regardless of the connection, thanks to OneOdio A70 headphones! You no longer have to worry about your music being interrupted by a cable falling out, as you can lock it into the headphones with a single movement. What's more, you can conveniently control the equipment with buttons located on one of the headphones. The noise cancellation technology that the headphones are equipped with will allow you to talk on the phone comfortably. From today your caller will always hear what you said.FunctionalityA70 headphones are not only functional and reliable equipment, but also full comfort. You will wear this equipment comfortably thanks to its adjustable headband and soft ear cups. In addition, you can conveniently fold it and give it to the bag, in which you will also safely transport your headphones.Included:A70 headphones6.35mm to 3.5mm cable x 13.5mm audio cable x 1USB charging cableUser manualBag ManufacturerOneOdioModelA70ConnectivityAudio cable 3.5 mm / 6.35 mm, Bluetooth 5.2Wireless operating timeUp to 50 hoursBatteryLi-ion, 950 mAhColorPink
