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This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will:Have an understanding of the basic toolbox of epigenetic regulationKnow how genetic and epigenetic information layers are interconnectedBe able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanismsUnderstand how misregulated epigenetic mechanisms can lead to disease

This undergraduate textbook first introduces basic electronic circuitry before explaining more advanced elements such as the Arithmetic Logic Unit, sequential circuits, and finally microprocessors. In keeping with this integrated and graduated approach, the authors then explain the relationship to first assembly programming, then higher-level languages, and finally computer organisation. Authors use the Raspberry Pi and ARM microprocessors for their explanations The material has been extensively class tested at TU Eindhoven by an experienced team of lecturers and researchers. This is a modern, holistic treatment of well-established topics, valuable for undergraduate students of computer science and electronics engineering and for self-study. The authors use the Raspberry Pi and ARM microprocessors for their explanations.

This comprehensive textbook provides detailed information on calving management in dairy and beef cattle. Enriched with diverse learning opportunities, it conveys the fundamentals of reproductive anatomy and physiology, parturition, birth complications and various obstetrical manoeuvres, as well as dam and calf care. In order to promote best practices in this specialized subject, the book covers all significant points from conception to calving and the perinatal period. Clear chapter structures, a wealth of illustrations and videos, obstetrical case studies, and question-and-answer lists round out the reading experience, making the book a unique source of information on how to support mother cows and obtain viable offspring. In addition, readers can download the free Springer Nature Flashcards App and benefit from 77 digital study questions to test their knowledge. Calving is a significant event in terms of providing care and nutrition for mother cows and calves. The reproductive health status in cattle farms is crucial to immediately initiate lactation and new conception. Assistance by technical personnel, dystocia and stillbirth occurrences can reach ca. 50%, 14% and 6% of parturitions, respectively. Hence, zootechnical and veterinary management of calving is of great importance for animal welfare. This textbook makes a valuable contribution to teaching and everyday practice in cattle medicine and obstetrics. Veterinary students, residents, practitioners and technical personnel will discover it to be a rich learning and reference resource.

This book provides a practically applicable manual to the utilisation of ultrasound in rheumatology. Each chapter includes high-quality diagrams of each anatomical region covered, accompanied by an ideal scan with written and pictorial demonstrations, as well as an ideal ultrasound image, that has been obtained via a high-end machine for optimal image quality. This systematic approach to describing the application of ultrasound in rheumatology enables the reader to develop a deep understanding of how to correctly make use of ultrasound technologies in their daily practice. Ultrasound in Rheumatology: A Practical Guide for Diagnosis is an easy to follow guide to the application of ultrasound in rheumatology and is a valuable resource for the trainee and practising rheumatologist seeking a guide on the correct use of ultrasound.

This book explores the fascinating and intimate relationship between music and physics. Over millennia, the playing of, and listening to music have stimulated creativity and curiosity in people all around the globe. Beginning with the basics, the authors first address the tonal systems of European-type music, comparing them with those of other, distant cultures. They analyze the physical principles of common musical instruments with emphasis on sound creation and particularly charisma. Modern research on the psychology of musical perception - the field known as psychoacoustics - is also described. The sound of orchestras in concert halls is discussed, and its psychoacoustic effects are explained. Finally, the authors touch upon the role of music for our mind and society. Throughout the book, interesting stories and anecdotes give insights into the musical activities of physicists and their interaction with composers and musicians.